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It is the proclamation of the Gospel, not argumentation, that transforms minds. See Give Them the Gospel.

The real reason that people will not accept reality is because they do not want to do the will of God.  God is love, so another way to say this is that they hate love.
 
Jesus said: "If you really want to obey God, you will know if what I teach comes from God or from me" 

Ravi Zacharias did two open forums in a university.  On the second night, one man told him that he had brought two Atheists in the night before who said that the arguments presented were so strong that they could not contend with them, but they were going to remain Atheists because that is what they prefer to be true.  
 
In listening to an unbeliever and drawing out his reasoning, the unbeliever finally came to his basic assumptions.  When asked why he believed his basic assumptions, the unbeliever looked a bid startled and blurted out, "I guess I'm making the whole thing up."  However, he decided to remain an Atheist because he didn't want God to rule over him.  
 
"The rejection of God is not an intellectual problem.  It is a moral problem." 
 
"To try to explain truth to him who loves it not is but to give him more plentiful material for misinterpretation."  George Macdonald  
 
"How frequently it is brought to our attention that nothing good can be done if the will is wrong! Reason alone fails to justify itself."  Richard M. Weaver  
 
"If we are not prepared to buy the truth at the cost of our own humbling we shall not receive it"  
 
"Lies have no price upon them. They are cheap and they abound everywhere. But for the truth there is always a price to pay." Watchman Nee  
 
"[God] has set a day when he will judge all the world's people with fairness. And he has chosen the man Jesus to do the judging for him. God has given proof of this to all of us by raising Jesus from death" (Acts 17:31).  
 
"There is a judge for the one who rejects me and does not accept my words; that very word which I spoke will condemn him at the last day" (John 12:48)  
 
"When we love others, we know that we belong to the truth, and we feel at ease in the presence of God" (1 John 3:19)  
 
"You will know the truth, and the truth will set you free" (John 8:32)